32 Acting Duos That Have Worked Together Multiple Times

Sometimes, all it takes is one joint appearance in a movie or television show for two popular actors to become known as an acting duo, and sometimes they prove to work so well together that they go on to star in even more projects together. We’ve come up with a list of 32 acting duos who have worked together multiple times, so you can see if you’ve watched all of the times these talented stars have been on screen with each other.

Tina Fey And Amy Poehler

Obviously, this funny duo began their most famed time together while starring on Saturday Night Live, but Tina Fey and Amy Poehler didn’t let the good times end there. The women were both in Mean Girls, starred in the movies Baby Mama and Sisters, and used their talents to great effect when co-hosting the Golden Globe Awards for several years.

Robert De Niro And Al Pacino

Two legendary actors make for a legendary acting duo, and while Robert De Niro and Al Pacino are frequently mentioned in the same breath, they’ve only been featured in four films together. Two of those movies, however, are absolutely the reason people often talk about them together as they count The Godfather Part II, Heat, Righteous Kill and The Irishman as their joint efforts.

Julia Roberts And George Clooney

Now, these two actually have made quite a few movies with one another, and largely with both in on-screen roles. Of course, it’s hard to forget that George Clooney and Julia Roberts are in all three of the Ocean’s Eleven films, but they’ve also starred in Confessions of a Dangerous Mind (which Clooney also directed), Money Monster and the 2022 rom-com Ticket to Paradise. The erstwhile Danny Ocean also produced August: Osage County, while Roberts starred.

Jane Fonda And Lily Tomlin

Frequently we see an acting duo together multiple times because they really are buddies in real life, and that’s true for Jane Fonda and Lily Tomlin. After first starring together in the 1980 hit 9 to 5 (with Dolly Parton, of course) they eventually re-teamed for the Netflix series Grace and Frankie (which ran for seven seasons), as well as the dark comedy Moving On and 80 for Brady.

Emma Stone And Ryan Gosling

This duo has produced some well-known and beloved comedies and dramas over the years, as Emma Stone and Ryan Gosling first starred together in Crazy, Stupid, Love in 2011, moving on to Gangster Squad in 2013 and the Oscar-winning musical La La Land in 2016. Stone even once said she couldn’t “imagine” her life without Gosling, so these two will probably be friends forever.

Salma Hayek And Antonio Banderas

Salma Hayek and Antonio Banderas sharing the screen in Desperado caused considerable heat, along with igniting a very real friendship, so it’s no surprise that they’ve now worked together a number of times. They’ve also been in the casts of Four Rooms, Frida, Once Upon a Time in Mexico, Spy Kids 3: Game Over, Hitman’s Wife’s Bodyguard and both Puss in Boots animated movies. That’s a lot!

Dwayne Johnson And Kevin Hart

We’ve already born witness to a rather lengthy history of Dwayne Johnson and Kevin Hart ripping on each other during their (apparently) laugh and roast-filled friendship, and the two megastars have, indeed, brought that chemistry to the big screen multiple times. The duo counts Central Intelligence, Jumanji: Welcome to the Jungle and its sequel, Hobbs & Shaw and DC League of Super-Pets as the titles they’ve appeared in together.

Matt Damon And Ben Affleck

If this isn’t a classic acting duo by now, there are none. Matt Damon and Ben Affleck have been “bizarrely close” friends since childhood, and they first joined forces to great effect by penning and starring in Good Will Hunting (after having both appeared in School Ties), which won them the Oscar for Best Original Screenplay. They also worked on Dogma in the 1990s, then, after nearly 25 years, they joined forces again to write and star in The Last Duel, and since then have also worked together on Air and the upcoming RIP for Netflix.

Denzel Washington And Don Cheadle

If only these two powerhouse stars had already been in more movies together…Denzel Washington and Don Cheadle’s first pairing was as P.I. Easy Rawlins and his loyal but unpredictable friend, Mouse, in 1995’s Devil in a Blue Dress. While their work in the film garnered critical acclaim, it would be over 15 years before they teamed again for Flight.

Sanaa Lathan And Taye Diggs

We should never underestimate the power of a franchise when it comes to popular on-screen pairings. Sanaa Lathan and Taye Diggs appeared in The Wood together in 1999 and then went on to star in The Best Man, its sequel and the Peacock mini-series, The Best Man: The Final Chapters. The duo also played the lead couple in the rom-com, Brown Sugar in 2002.

Scarlett Johansson And Chris Evans

Co-starring in a franchise with the same people will take an acting duo far, but Scarlett Johansson and Chris Evans have surpassed even the typical standard where that’s concerned. Thanks to their joint time in the Marvel Cinematic Universe, they’ve appeared in a whopping seven movies together (including their mid-end credits cameo in Captain Marvel), and prior to their time as blockbuster movie-making superheroes they starred in The Perfect Score and The Nanny Diaries, bringing their current total to nine.

Anthony Mackie And Chris Evans

If you did enjoy many of those MCU movies, then you know that Chris Evans rubbed elbows with Anthony Mackie quite a bit there. But, did you also know that the two have been in XX non-Marvel movies together? Playing It Cool, What’s Your Number, and Ghosted also star/feature both actors and if you add in all their shared time in tights on screen, their total is also at nine.

Emily Blunt And Dwayne Johnson

The first time was a hit, so why not join forces again, right? Emily Blunt and Dwayne Johnson famously delivered winning chemistry in Jungle Cruise, and are coming back together for the upcoming drama The Smashing Machine. The two are also said to be willing to return for Jungle Cruise 2, whenever that can finally get off the ground.

Chris Pine And Ben Foster

The third time has been the charm so far for Chris Pine and Ben Foster. The duo famously portrayed bank-robbing brothers in Hell or High Water, joined up for The Finest Hours, and made it a three-peat in 2022 for The Contractor.

Margot Robbie And Will Smith

If it seemed that there could have been a little something extra going on between Margot Robbie’s Harley Quinn and Will Smith’s Deadshot when you watched 2016’s Suicide Squad, then it might have been because you picked up on the chemistry the duo first built in Focus from the year before.

Margot Robbie And Brad Pitt

This big screen coupling made quite a showing for themselves across less than a decade, as Margot Robbie and Brad Pitt have starred in The Big Short, Once Upon a Time…in Hollywood and Babylon. 

Margot Robbie And Leonardo DiCaprio

Just imagine, had it not been for this pairing, we might not have the megastar who is Barbie actor/producer Margot Robbie right now. Her role in Wolf of Wall Street as the second wife of Leonardo DiCaprio’s corrupt fraudster propelled her career, and by the time they starred in Once Upon a Time…in Hollywood together Robbie was a major star.

Halle Berry And Hugh Jackman

We, again, have a superhero franchise to thank for bringing two great talents together, as Oscar winner Halle Berry and Hugh Jackman both have four of the X-Men movies among their credits. The duo also starred in Swordfish and Movie 43.

Awkwafina And Michelle Yeoh

This duo counts two megahits in their joint credits, with Awkwafina and Everything Everywhere All At Once Oscar winner Michelle Yeoh both having starred in Crazy Rich Asians (and we’re still waiting for that rom-com sequel) and the MCU entry Shang-Chi and the Legend of the Ten Rings.

Michelle Yeoh And Jackie Chan

Michelle Yeoh has been a star for several decades, and part of that reason is because of her breakout role in the 1992’s Supercop, which also starred Jackie Chan. But, they’ve made a number of other films with each other, including Supercop 2, and Hong Kong action films Twinkle, Twinkle, Lucky Stars, Project S, and both voiced characters in Kung Fu Panda 2, along with having starred in a 1984 watch commercial together.

Angela Bassett And Laurence Fishburne

While Angela Bassett and Laurence Fishburne were famously nominated for Oscars for their lead roles as Tina Turner and Ike Turner in 1993’s What’s Love Got to Do with It?, the duo was actually first together on screen for Boyz n the Hood in ‘91. They then later teamed up for Akeela and the Bee in 2006.

Julia Roberts And Richard Gere

If this isn’t a famous acting duo, then none are, despite their only making two movies with each other. Of course, Julia Roberts and Richard Gere starred in the mega-hit classic rom-com Pretty Woman and teamed up again for Runaway Bride in 1999.

Jennifer Aniston And Jason Bateman

For a while there, Jennifer Aniston and Jason Bateman, who are friends in real life, were kinda on a roll. Their first joint film was The Break-Up in 2006, and since then they’ve filmed four additional movies with one another: The Switch, Horrible Bosses and its sequel, and 2016’s Office Christmas Party.

Kate Hudson And Matthew McConaughey

Who can forget the glorious chemistry created by Kate Hudson and Matthew McConaughey in How to Lose A Guy in 10 Days? No one, that’s who! This is why they made a second rom-com, Fool’s Gold, just five years later.

Kirsten Dunst And Jesse Plemons

It’s not unusual for an acting duo to become friends in real life, but Kirsten Dunst and Jesse Plemons took that a few steps further after working on the TV series Fargo together. Not only have they since starred in the film The Power of the Dog (which netted each their first Oscar nomination) and the A24 drama Civil War, but they married in 2022 and have two sons.

Meg Ryan And Tom Hanks

We could hardly leave Meg Ryan and Tom Hanks off of this list, as the famed actors have co-starred in two of the biggest romantic comedies of all time. Everyone knows them for making Sleepless in Seattle and You’ve Got Mail hits, but before all of that, they led one of the weirder rom-coms made with Joe Versus the Volcano, and reunited for the 2016 drama Ithaca, which Ryan directed.

Drew Barrymore And Adam Sandler

People often mention Drew Barrymore and Adam Sandler as an acting duo they want to see more of and with good reason. The two have made magic in the classics The Wedding Singer, 50 First Dates and Blended.

Adam Sandler And Chris Rock

This pairing goes back decades, to the time when Adam Sandler and Chris Rock starred on Saturday Night Live together in the ‘90s. Since then, the real-life buddies have appeared in seven movies together, with The Longest Yard, Grown Ups and its sequel, The Week Of and Top Five counted among that number.

George Clooney And Brad Pitt

Of course, George Clooney and Brad Pitt helped to make the Ocean’s Eleven franchise a hit, but the friends additionally teamed up for the live TV movie 8, Confessions of a Dangerous Mind (which Clooney directed), Burn After Reading and the 2024 films If and Wolfs.

Keegan-Michael Key And Jordan Peele

The duo of Keegan-Michael Key and Jordan Peele, who first became recognizable during their time on MadTV, eventually went on to their own acclaimed sketch comedy series, Key and Peele. But, while making names for themselves on other series and in a number of movies, they continue to work with one another on projects like Keanu, Toy Story 4 and Wendell & Wild.

Awkwafina And Simu Liu

It was the MCU that first brought Awkwafina and Simu Liu together in the hit film Shang-Chi and the Legend of the Ten Rings, and while we’re still waiting to see when that franchise will bring them back together, 2024 saw them team up again for the action comedy, Jackpot!.

Jane Fonda And Robert Redford

Dedicated film fans probably know that legends Jane Fonda and Robert Redford starred together in Barefoot in the Park and The Electric Horseman, but their joint movie appearances do go beyond that. They also starred in The Chase in ‘66 and reunited for Our Souls at Night in 2017, and both had their film debuts in 1960’s Tall Story.

As you can see, film history is packed with acting duos who’ve worked together more than once, and that will probably always be the case.